iPTMnet Report for P04070 (PROC)
Protein Information
| UniProt AC / UniProt ID | P04070 / PROC_HUMAN |
| Protein Name | Vitamin K-dependent protein C precursor |
| Gene Name | Name: PROC |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P04070 |
| PRO Name | vitamin K-dependent protein C (human) |
| Definition | A vitamin K-dependent protein C that is encoded in the genome of human. |
| Short Label | hPROC |
| Category | organism-gene |
DAG ViewP04070 (PROC) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| T19 | O-Glycosylation | score2 | GlyGen UniProt | 22171320 | ||
| N139 | N-Glycosylation | score3 | GlyGen | 29741879, 19343721, 25326145 | ||
| K233 | Acetylation | score1 | PhosphoSitePlus | |||
| K234 | Acetylation | score1 | PhosphoSitePlus | |||
| N290 | N-Glycosylation | score4 | GlyGen UniProt | 16335952, 34725484, 19343721, ... | ||
| S347 | Phosphorylation | score1 | UniProt | 26091039 | ||
| N355 | N-Glycosylation | score4 | GlyGen UniProt | 19343721, 2991887 | ||
| N371 | N-Glycosylation | score4 | GlyGen UniProt | 19343721, 1694179, 8130392, ... | ||
| S382 | O-Glycosylation | score1 | GlyGen | 30459171 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K233 | N233 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S347 | N347 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S347 | R347 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S382 | Y382 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
