iPTMnet Report P02790 HPX

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P02790 / HEMO_HUMAN
Protein Name	Hemopexin precursor
Gene Name	Name: HPX
Organism	Homo sapiens (Human)

PRO ID	PR:P02790 DAG View
PRO Name	hemopexin (human)
Definition	A hemopexin that is encoded in the genome of human.
Short Label	hHPX
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P02790 (HPX) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	T24	O-Glycosylation		score4	GlyGen UniProt	6371807, 30459171, 23234360, ...19838169, 6510521, 24417605, 26598643
	T29	O-Glycosylation		score2	GlyGen UniProt	30459171, 23234360, 26598643
	S30	O-Glycosylation		score1	GlyGen	30459171, 26598643
	T40	O-Glycosylation		score1	GlyGen	34725484, 30459171
	N64	N-Glycosylation		score4	GlyGen UniProt	16335952, 34725484, 30237853, ...6371807, 23090970, 29391424, 19838169, 25265424, 29741879, 29671580
	S87	Phosphorylation		score1	IEDB	35494241
	N187	N-Glycosylation		score4	GlyGen UniProt	16335952, 34725484, 24530628, ...25265424, 19159218, 6371807, 14760718, 29391424, 32125861, 15084671, 19139490, 19838169, 24279413, 16740002, 18514042, 29741879, 29427759, 29671580, 29992770, 24841998, 30237853
	C200	Methylation		score1	IEDB	29786170, 31844290
	C200	S-Nitrosylation		score0	dbSNO	25040305
	Y220	Phosphorylation		score1	PhosphoSitePlus
	N240	N-Glycosylation		score4	GlyGen UniProt	14760718, 6510521, 32125861, ...6371807
	N246	N-Glycosylation		score4	GlyGen UniProt	6371807, 14760718, 6510521, ...32125861, 24417605
	Y341	Phosphorylation		score1	PhosphoSitePlus
	T351	O-Glycosylation		score1	GlyGen	30459171
	C366	S-Nitrosylation		score0	dbSNO	25040305
	K386	Acetylation		score1	PhosphoSitePlus
	N416	N-Glycosylation		score1	GlyGen	23090970
	N453	N-Glycosylation		score4	GlyGen UniProt	34725484, 24530628, 16740002, ...32125861, 19159218, 6371807, 23090970, 26791533, 15084671, 19139490, 19838169, 24279413, 25265424, 18514042, 29741879, 29671580, 24417605, 24841998, 30237853

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N64	N-Glycosylation		score1	PRO	19838169, 29671580
	N187	N-Glycosylation		score1	PRO	19838169, 29671580, 24841998
	N453	N-Glycosylation		score1	PRO	24279413, 19838169, 26791533, ...29671580, 24841998

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T24	S24	Biomuta		DOID:1324 / lung cancer [ cosmic, icgc ]