iPTMnet Report for P02743 (APCS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P02743 / SAMP_HUMAN
Protein Name Serum amyloid P-component precursor
Gene Name Name: APCS
Synonyms:PTX2;
Organism Homo sapiens (Human)

PRO ID PR:P02743
DAG View
PRO Name serum amyloid P-component (human)
Definition A serum amyloid P-component that is encoded in the genome of human.
Short Label hAPCS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P02743 (APCS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T12 Phosphorylation HPRD   PhosphoSitePlus 19413330
S13 Phosphorylation HPRD   PhosphoSitePlus 19413330
T21 Phosphorylation HPRD   PhosphoSitePlus 19413330
N51 N-Glycosylation GlyGen 16335952, 23090970, 29741879, ...19159218, 8202534
Y59 Phosphorylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
Y142 Phosphorylation PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
K162 Acetylation PhosphoSitePlus
T195 O-Glycosylation GlyGen 30459171
Site PTM Type PTM Enzyme Score Source PMID
N51 N-Glycosylation PRO 8202534


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T12 N12 Biomuta DOID:3571 / liver cancer [ cosmic ]
S13 N13 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
N51 K51 Biomuta DOID:5158 / pleural cancer [ cosmic ]
K162 R162 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ]
K162 T162 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K162 M162 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T195 P195 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]