iPTMnet Report for P02675 (FGB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P02675 / FIBB_HUMAN
Protein Name Fibrinogen beta chain precursor
Gene Name Name: FGB
Organism Homo sapiens (Human)

PRO ID PR:P02675
DAG View
PRO Name fibrinogen beta chain (human)
Definition A fibrinogen beta chain that is encoded in the genome of human.
Short Label hFGB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P02675 (FGB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N34 Methylation IEDB 28649982
S58 O-Glycosylation GlyGen 30459171, 26598643
S58 Phosphorylation PhosphoSitePlus
Y71 Phosphorylation PhosphoSitePlus
T108 O-Glycosylation GlyGen 30459171, 25813380
S138 Phosphorylation PhosphoSitePlus
Y172 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
Y182 Phosphorylation PhosphoSitePlus
K208 Acetylation PhosphoSitePlus
C227 S-Nitrosylation dbSNO 25040305
T228 Phosphorylation PhosphoSitePlus
C231 S-Nitrosylation dbSNO 25040305
S237 Phosphorylation PhosphoSitePlus
Y255 Phosphorylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
Y266 Phosphorylation PhosphoSitePlus
Y269 Phosphorylation PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
Y299 Phosphorylation PhosphoSitePlus
K300 Acetylation PhosphoSitePlus
K313 Acetylation PhosphoSitePlus
N314 N-Glycosylation GlyGen 23090970
Y315 Phosphorylation PhosphoSitePlus
C316 S-Nitrosylation dbSNO 25040305
T333 Phosphorylation PhosphoSitePlus
T338 Phosphorylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
T360 O-Glycosylation GlyGen 25813380
Y368 Phosphorylation PhosphoSitePlus
S371 Phosphorylation PhosphoSitePlus
N394 N-Glycosylation GlyGen   UniProt 16335952, 7107587, 32125861, ...19159218, 23090970, 16263699, 29741879, 10074346, 29671580, 9628725
T396 Phosphorylation PhosphoSitePlus
Y408 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
N435 N-Glycosylation GlyGen 23090970
Y452 Phosphorylation PhosphoSitePlus
K471 Acetylation PhosphoSitePlus
Y475 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N394 N-Glycosylation PRO 29671580, 7107587


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S138 F138 Biomuta DOID:4159 / skin cancer [ cosmic ]
S173 Y173 Biomuta DOID:263 / kidney cancer [ cosmic ]
C227 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
C231 * Biomuta [ cosmic ]
S237 P237 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S289 I289 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K313 N313 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
Y368 C368 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S371 L371 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K471 T471 Biomuta [ cosmic ]
K471 R471 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K471 N471 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]