iPTMnet Report for P02461 (COL3A1)
Protein Information
UniProt AC / UniProt ID | P02461 / CO3A1_HUMAN |
Protein Name | Collagen alpha-1(III) chain precursor |
Gene Name | Name: COL3A1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P02461 |
PRO Name | collagen alpha-1(III) chain (human) |
Definition | A collagen alpha-1(III) chain that is encoded in the genome of human. |
Short Label | hCOL3A1 |
Category | organism-gene |
P02461 (COL3A1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T96 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
T146 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
S152 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
K757 | Ubiquitination | score1 | PhosphoSitePlus | |||
S916 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1145 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533 | ||
Y1220 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1237 | Phosphorylation | score1 | PhosphoSitePlus | |||
N1367 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
Y1370 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y1378 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17287340 | ||
S1383 | Phosphorylation | score1 | phospho.ELM | 17287340 | ||
K1387 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T96 | S96 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S143 | L143 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S152 | T152 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S152 | Y152 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ] | |
Y1220 | N1220 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
Y1220 | F1220 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
Y1370 | * | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K1387 | N1387 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |