Protein Information

Cytoscape View


UniProt AC / UniProt ID P00403 / COX2_HUMAN
Protein Name Cytochrome c oxidase subunit 2
Gene Name Name: MT-CO2
Synonyms:COII,COX2;
Organism Homo sapiens (Human)

PRO ID PR:P00403
DAG View
PRO Name cytochrome c oxidase subunit 2 (human)
Definition A cytochrome c oxidase subunit 2 that is encoded in the genome of human.
Short Label hMT-CO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P00403 (MT-CO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R82 Methylation PhosphoSitePlus
N119 Methylation IEDB 32357974
D158 Methylation IEDB 30410026
K171 Ubiquitination PhosphoSitePlus
C196 S-Nitrosylation dbSNO 15561762, 22178444
C200 S-Nitrosylation dbSNO 15561762, 22178444


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R82 H82 Biomuta DOID:263 / kidney cancer [ cosmic ]
N119 S119 Biomuta DOID:2531 / hematologic cancer [ cosmic ]