iPTMnet Report for O96005 (CLPTM1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O96005 / CLPT1_HUMAN
Protein Name Putative lipid scramblase CLPTM1
Gene Name Name: CLPTM1
Organism Homo sapiens (Human)

PRO ID PR:O96005
DAG View
PRO Name putative lipid scramblase CLPTM1 (human)
Definition A putative lipid scramblase CLPTM1 that is encoded in the genome of human.
Short Label hCLPTM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O96005 (CLPTM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 25489052, 22814378
K209 Ubiquitination PhosphoSitePlus
T213 Phosphorylation PhosphoSitePlus
T216 Phosphorylation PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
N241 N-Glycosylation GlyGen 24190977
N245 N-Glycosylation GlyGen 24190977
K267 Ubiquitination PhosphoSitePlus
Y275 Phosphorylation PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus
N295 N-Glycosylation GlyGen   UniProt 16263699, 29741879, 19159218, ...24190977
S297 O-Glycosylation GlyGen 33214551, 34725712, 34019948, ...35254053
S306 Phosphorylation PhosphoSitePlus
S311 Phosphorylation PhosphoSitePlus
T323 O-Glycosylation GlyGen 25813380
K324 Ubiquitination PhosphoSitePlus
S338 Phosphorylation PhosphoSitePlus
K436 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus   UniProt 24275569
T616 Phosphorylation PhosphoSitePlus
T622 Phosphorylation PhosphoSitePlus
T628 Phosphorylation PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T216 A216 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
N245 S245 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S306 F306 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K458 N458 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T616 I616 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T622 M622 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
T622 R622 Biomuta DOID:1324 / lung cancer [ cosmic ]