iPTMnet Report for O95996 (APC2)
Protein Information
UniProt AC / UniProt ID | O95996 / APCL_HUMAN |
Protein Name | Adenomatous polyposis coli protein 2 |
Gene Name | Name: APC2 Synonyms:APCL; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95996 |
PRO Name | adenomatous polyposis coli protein 2 (human) |
Definition | An adenomatous polyposis coli protein 2 that is encoded in the genome of human. |
Short Label | hAPC2 |
Category | organism-gene |
O95996 (APC2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S4 | O-Glycosylation | score1 | GlyGen | 31492838 | ||
S108 | Phosphorylation | score1 | PhosphoSitePlus | |||
S113 | Phosphorylation | score1 | PhosphoSitePlus | |||
S116 | Phosphorylation | score1 | PhosphoSitePlus | |||
S304 | Phosphorylation | score1 | PhosphoSitePlus | |||
S510 | Phosphorylation | score1 | PhosphoSitePlus | |||
S511 | Phosphorylation | score1 | PhosphoSitePlus | |||
S517 | Phosphorylation | score1 | PhosphoSitePlus | |||
S678 | Phosphorylation | score1 | PhosphoSitePlus | |||
S873 | Phosphorylation | score1 | PhosphoSitePlus | |||
S875 | Phosphorylation | score1 | PhosphoSitePlus | |||
S876 | Phosphorylation | score1 | PhosphoSitePlus | |||
S952 | Phosphorylation | score1 | IEDB | 35494241 | ||
T998 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y999 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1052 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1068 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1148 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1160 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1164 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1167 | Phosphorylation | score1 | PhosphoSitePlus | |||
R1427 | Methylation | score1 | PhosphoSitePlus | |||
R1431 | Methylation | score1 | PhosphoSitePlus | |||
S1455 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
S1675 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1834 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1861 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1863 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1883 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2009 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2016 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2025 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2041 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2101 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2203 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2204 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2205 | Phosphorylation | score1 | PhosphoSitePlus | |||
S2206 | Phosphorylation | score1 | PhosphoSitePlus | |||
T2211 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S952 | L952 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
Y999 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] | |
R1431 | H1431 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
R1431 | C1431 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] |