iPTMnet Report for O95970 (LGI1)
Protein Information
UniProt AC / UniProt ID | O95970 / LGI1_HUMAN |
Protein Name | Leucine-rich glioma-inactivated protein 1 precursor |
Gene Name | Name: LGI1 Synonyms:EPT;ORFNames:UNQ775/PRO1569; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95970 |
PRO Name | leucine-rich glioma-inactivated protein 1 (human) |
Definition | A leucine-rich glioma-inactivated protein 1 that is encoded in the genome of human. |
Short Label | hLGI1 |
Category | organism-gene |
O95970 (LGI1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y21 | Phosphorylation | score1 | PhosphoSitePlus | |||
S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
T32 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 35494241 | ||
K160 | Ubiquitination | score1 | PhosphoSitePlus | |||
S464 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y21 | H21 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S27 | Y27 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S464 | L464 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] |