Protein Information

Cytoscape View


UniProt AC / UniProt ID O95970 / LGI1_HUMAN
Protein Name Leucine-rich glioma-inactivated protein 1 precursor
Gene Name Name: LGI1
Synonyms:EPT;ORFNames:UNQ775/PRO1569;
Organism Homo sapiens (Human)

PRO ID PR:O95970
DAG View
PRO Name leucine-rich glioma-inactivated protein 1 (human)
Definition A leucine-rich glioma-inactivated protein 1 that is encoded in the genome of human.
Short Label hLGI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95970 (LGI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y21 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
T32 Phosphorylation IEDB   PhosphoSitePlus 35494241
K160 Ubiquitination PhosphoSitePlus
S464 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y21 H21 Biomuta DOID:3571 / liver cancer [ cosmic ]
S27 Y27 Biomuta DOID:363 / uterine cancer [ icgc ]
S464 L464 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]