Protein Information

Cytoscape View


UniProt AC / UniProt ID O95948 / ONEC2_HUMAN
Protein Name One cut domain family member 2
Gene Name Name: ONECUT2
Synonyms:HNF6B;
Organism Homo sapiens (Human)

PRO ID PR:O95948
DAG View
PRO Name one cut domain family member 2 (human)
Definition An one cut domain family member 2 that is encoded in the genome of human.
Short Label hONECUT2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95948 (ONECUT2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R79 Methylation PhosphoSitePlus
T86 O-Glycosylation GlyGen 34846842
T93 O-Glycosylation GlyGen 35254053
S259 Phosphorylation PhosphoSitePlus
T335 Phosphorylation PhosphoSitePlus
Y349 Phosphorylation PhosphoSitePlus
T367 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S259 I259 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y349 H349 Biomuta DOID:1324 / lung cancer [ cosmic ]