iPTMnet Report for O95816 (BAG2)
Protein Information
| UniProt AC / UniProt ID | O95816 / BAG2_HUMAN |
| Protein Name | BAG family molecular chaperone regulator 2 |
| Gene Name | Name: BAG2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O95816 |
| PRO Name | BAG family molecular chaperone regulator 2 (human) |
| Definition | A BAG family molecular chaperone regulator 2 that is encoded in the genome of human. |
| Short Label | hBAG2 |
| Category | organism-gene |
O95816 (BAG2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 22814378 | ||
| K5 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S20 | Phosphorylation | P49137 (MAPKAPK2) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 15271996, 20068231 | |
| S31 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S73 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 23186163 | ||
| K111 | Acetylation | score1 | PhosphoSitePlus | |||
| K111 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S143 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C162 | S-Nitrosylation | score0 | dbSNO | 19483679 | ||
| K168 | Acetylation | score1 | PhosphoSitePlus | |||
| K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K169 | Acetylation | score1 | PhosphoSitePlus | |||
| T176 | O-Glycosylation | score1 | GlyGen | 23301498, 34725712, 34019948, ... | ||
| T176 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K186 | Acetylation | score1 | PhosphoSitePlus | |||
| K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K195 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K200 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T201 | Phosphorylation | score1 | PhosphoSitePlus |
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S20 | Phosphorylation | P49137 (MAPKAPK2) | score2 | HPRD | 19651622, 15271996, 20068231 | |
| S73 | Phosphorylation | score0 | HPRD | 18691976 | ||
| S133 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S137 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y139 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S140 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S143 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S144 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K123 | T123 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S144 | C144 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
| K168 | N168 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View