iPTMnet Report for O95373 (IPO7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95373 / IPO7_HUMAN
Protein Name Importin-7
Gene Name Name: IPO7
Synonyms:RANBP7;
Organism Homo sapiens (Human)

PRO ID PR:O95373
DAG View
PRO Name importin-7 (human)
Definition An importin-7 that is encoded in the genome of human.
Short Label hIPO7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95373 (IPO7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378, 12665801, ...22223895
T5 O-Glycosylation GlyGen 23301498, 16408927, 33214551, ...35138101, 30379171, 34725712, 29351928, 34019948, 35083852, 32119511
R11 Methylation PhosphoSitePlus
T43 Phosphorylation HPRD 20068231
Y59 Phosphorylation PhosphoSitePlus
S102 O-Glycosylation GlyGen 23301498, 16408927, 33214551, ...35138101, 30379171, 34725712, 29351928, 34019948, 35083852, 32119511
S102 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
Y309 Phosphorylation PhosphoSitePlus
Y311 Phosphorylation HPRD   PhosphoSitePlus 15592455
K312 Ubiquitination PhosphoSitePlus
Y316 Phosphorylation PhosphoSitePlus
K379 Methylation PhosphoSitePlus
K403 Methylation PhosphoSitePlus
C415 S-Nitrosylation dbSNO 26338901
K429 Ubiquitination PhosphoSitePlus
S438 Phosphorylation HPRD   PhosphoSitePlus 20068231
K445 Methylation PhosphoSitePlus
K446 Methylation PhosphoSitePlus
K489 Ubiquitination PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
C722 Methylation IEDB 31844290
K724 Ubiquitination PhosphoSitePlus
T775 Phosphorylation PhosphoSitePlus
Y876 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18669648, 17081983
S886 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
T898 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
S903 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983
Y915 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18691976, 18669648, 17081983
Y959 Phosphorylation PhosphoSitePlus
K990 Ubiquitination PhosphoSitePlus
K1009 Ubiquitination PhosphoSitePlus
K1013 Ubiquitination PhosphoSitePlus
Y1017 Phosphorylation PhosphoSitePlus
K1018 Ubiquitination PhosphoSitePlus
S1020 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y59 F59 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
Y311 C311 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y316 C316 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K429 N429 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S438 F438 Biomuta DOID:1319 / brain cancer [ cosmic ]