iPTMnet Report for O95256 (IL18RAP)
Protein Information
UniProt AC / UniProt ID | O95256 / I18RA_HUMAN |
Protein Name | Interleukin-18 receptor accessory protein precursor |
Gene Name | Name: IL18RAP Synonyms:IL1R7; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95256 |
PRO Name | interleukin-18 receptor accessory protein (human) |
Definition | An interleukin-18 receptor accessory protein that is encoded in the genome of human. |
Short Label | hIL18RAP |
Category | organism-gene |
O95256 (IL18RAP) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N119 | N-Glycosylation | score3 | GlyGen UniProt | 25500532 | ||
S133 | Phosphorylation | score1 | PhosphoSitePlus | |||
N152 | N-Glycosylation | score3 | GlyGen UniProt | 25500532 | ||
S294 | Phosphorylation | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
S342 | Phosphorylation | score1 | PhosphoSitePlus | |||
N345 | N-Glycosylation | score3 | GlyGen UniProt | 25500532 | ||
T401 | Phosphorylation | score1 | PhosphoSitePlus | |||
S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
K543 | Acetylation | score1 | PhosphoSitePlus | |||
K554 | Acetylation | score1 | PhosphoSitePlus | |||
K554 | Methylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S133 | R133 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S294 | C294 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S294 | Y294 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S307 | G307 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S342 | P342 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
T401 | M401 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
T401 | A401 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
S469 | T469 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |