iPTMnet Report for O95197 (RTN3)
Protein Information
UniProt AC / UniProt ID | O95197 / RTN3_HUMAN |
Protein Name | Reticulon-3 |
Gene Name | Name: RTN3 Synonyms:ASYIP,NSPL2; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O95197 |
PRO Name | reticulon-3 (human) |
Definition | A reticulon-3 that is encoded in the genome of human. |
Short Label | hRTN3 |
Category | organism-gene |
O95197 (RTN3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 21406692, 22223895, ... | ||
T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S30 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 23186163, 17081983 | ||
S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S229 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
S234 | Phosphorylation | score1 | PhosphoSitePlus | |||
S243 | Phosphorylation | score1 | PhosphoSitePlus | |||
S246 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S268 | Phosphorylation | score1 | PhosphoSitePlus | |||
S316 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T318 | Phosphorylation | score1 | PhosphoSitePlus | |||
S326 | Phosphorylation | score1 | PhosphoSitePlus | |||
K386 | Ubiquitination | score1 | PhosphoSitePlus | |||
T387 | Phosphorylation | score1 | PhosphoSitePlus | |||
S391 | O-Glycosylation | score1 | GlyGen | 29351928, 35083852, 33465208, ... | ||
S395 | Phosphorylation | score1 | PhosphoSitePlus | |||
T396 | O-Glycosylation | score1 | GlyGen | 29351928, 35083852, 33465208, ... | ||
T396 | Phosphorylation | score1 | PhosphoSitePlus | |||
T399 | O-Glycosylation | score1 | GlyGen | 29351928, 35083852, 33465208, ... | ||
K419 | Ubiquitination | score1 | PhosphoSitePlus | |||
K434 | Acetylation | score1 | PhosphoSitePlus | |||
S453 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T467 | Phosphorylation | score1 | PhosphoSitePlus | |||
S526 | O-Glycosylation | score1 | GlyGen | 29351928, 35083852, 33465208, ... | ||
K540 | Methylation | score1 | PhosphoSitePlus | |||
S560 | Phosphorylation | score1 | PhosphoSitePlus | |||
S575 | Phosphorylation | score1 | PhosphoSitePlus | |||
S591 | Phosphorylation | score1 | PhosphoSitePlus | |||
S613 | Phosphorylation | score1 | PhosphoSitePlus | |||
T614 | Phosphorylation | score1 | PhosphoSitePlus | |||
S616 | Phosphorylation | score1 | PhosphoSitePlus | |||
S649 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S650 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
S678 | O-Glycosylation | score1 | GlyGen | 29351928, 35083852, 33465208, ... | ||
T687 | Phosphorylation | score1 | PhosphoSitePlus | |||
S698 | Phosphorylation | score1 | PhosphoSitePlus | |||
S708 | Phosphorylation | score1 | PhosphoSitePlus | |||
R754 | Methylation | score1 | PhosphoSitePlus | |||
T811 | Phosphorylation | score1 | PhosphoSitePlus | |||
D956 | Methylation | score1 | IEDB | 29786170 | ||
Y969 | Phosphorylation | score1 | PhosphoSitePlus | |||
K998 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1004 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1013 | Acetylation | score1 | PhosphoSitePlus | |||
K1013 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1018 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1022 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T8 | Phosphorylation | score0 | HPRD | 18491316 | ||
S23 | Phosphorylation | score0 | HPRD | 20068231 | ||
S30 | Phosphorylation | score0 | HPRD | 19413330, 18578522, 17081983, ... | ||
T39 | Phosphorylation | score0 | HPRD | 20068231 | ||
S210 | Phosphorylation | score0 | HPRD | 19413330 | ||
S227 | Phosphorylation | score0 | HPRD | 19651622, 18578522 | ||
S541 | Phosphorylation | score0 | HPRD | 17081983 | ||
S630 | Phosphorylation | score0 | HPRD | 18669648 | ||
S631 | Phosphorylation | score0 | HPRD | 18669648 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T8 | Phosphorylation | score0 | HPRD | 18491316 | ||
S23 | Phosphorylation | score0 | HPRD | 20068231 | ||
S30 | Phosphorylation | score0 | HPRD | 19413330, 18578522, 17081983, ... | ||
T39 | Phosphorylation | score0 | HPRD | 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T8 | Phosphorylation | score0 | HPRD | 18491316 | ||
S23 | Phosphorylation | score0 | HPRD | 20068231 | ||
S30 | Phosphorylation | score0 | HPRD | 19413330, 18578522, 17081983, ... | ||
T39 | Phosphorylation | score0 | HPRD | 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T8 | Phosphorylation | score0 | HPRD | 18491316 | ||
S23 | Phosphorylation | score0 | HPRD | 20068231 | ||
S30 | Phosphorylation | score0 | HPRD | 19413330, 18578522, 17081983, ... | ||
T39 | Phosphorylation | score0 | HPRD | 20068231 | ||
K206 | Ubiquitination | score1 | PhosphoSitePlus | |||
S218 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K152 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K206 | R206 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S234 | L234 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
S243 | F243 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
S316 | L316 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S391 | Y391 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
S541 | N541 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S560 | N560 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S616 | F616 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S631 | F631 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S650 | F650 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
D956 | E956 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
D956 | H956 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K1022 | E1022 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |