iPTMnet Report for O95067 (CCNB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O95067 / CCNB2_HUMAN
Protein Name G2/mitotic-specific cyclin-B2
Gene Name Name: CCNB2
Organism Homo sapiens (Human)

PRO ID PR:O95067
DAG View
PRO Name G2/mitotic-specific cyclin-B2 (human)
Definition A G2/mitotic-specific cyclin-B2 that is encoded in the genome of human.
Short Label hCCNB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O95067 (CCNB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T8 Phosphorylation PhosphoSitePlus   UniProt 23186163
S10 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus   UniProt 23186163
T18 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus   UniProt 23186163
K79 Ubiquitination PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
S92 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19664994, ...19007248, 18669648, 20068231
T94 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 18669648
S99 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648
K101 Ubiquitination PhosphoSitePlus
C131 Methylation IEDB 31844290
C190 Methylation IEDB 31844290
S204 Phosphorylation HPRD   PhosphoSitePlus 18691976
S220 Phosphorylation PhosphoSitePlus
K258 Ubiquitination PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
Y298 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K328 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
K360 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
Y368 Phosphorylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
K388 Ubiquitination PhosphoSitePlus
S392 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 23186163
S398 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 19369195, ...18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 R11 Biomuta DOID:263 / kidney cancer [ cosmic ]
K25 N25 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S92 F92 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S204 F204 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S274 P274 Biomuta DOID:9256 / colorectal cancer [ icgc ]
Y368 H368 Biomuta DOID:363 / uterine cancer [ cosmic ]
S398 P398 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]