iPTMnet Report for O94911 (ABCA8)
Protein Information
UniProt AC / UniProt ID | O94911 / ABCA8_HUMAN |
Protein Name | ABC-type organic anion transporter ABCA8 |
Gene Name | Name: ABCA8 Synonyms:KIAA0822; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O94911 |
PRO Name | ABC-type organic anion transporter ABCA8 (human) |
Definition | An ABC-type organic anion transporter ABCA8 that is encoded in the genome of human. |
Short Label | hABCA8 |
Category | organism-gene |
O94911 (ABCA8) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C9 | Methylation | score1 | IEDB | 31844290 | ||
K102 | Ubiquitination | score1 | PhosphoSitePlus | |||
K249 | Acetylation | score1 | PhosphoSitePlus | |||
T256 | Phosphorylation | score1 | PhosphoSitePlus | |||
K811 | Ubiquitination | score1 | PhosphoSitePlus | |||
K830 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1173 | Phosphorylation | score1 | IEDB | 32387766 | ||
T1399 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1547 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1581 | Phosphorylation | score1 | IEDB | 32387766 | ||
S1610 | Phosphorylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T256 | Phosphorylation | score0 | HPRD | 20068231 | ||
K595 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1507 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K595 | N595 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
K830 | N830 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S1581 | N1581 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |