iPTMnet Report for O94763 (URI1)
Protein Information
UniProt AC / UniProt ID | O94763 / RMP_HUMAN |
Protein Name | Unconventional prefoldin RPB5 interactor 1 |
Gene Name | Name: URI1 Synonyms:C19orf2,NNX3,PPP1R19,RMP,URI; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O94763 |
PRO Name | unconventional prefoldin RPB5 interactor 1 (human) |
Definition | An unconventional prefoldin RPB5 interactor 1 that is encoded in the genome of human. |
Short Label | hURI1 |
Category | organism-gene |
O94763 (URI1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
S13 | Phosphorylation | score1 | PhosphoSitePlus | |||
K53 | Ubiquitination | score1 | PhosphoSitePlus | |||
K172 | Methylation | score1 | PhosphoSitePlus | |||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
T241 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 23667685 | ||
T242 | Phosphorylation | score1 | PhosphoSitePlus | |||
S243 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 23667685 | ||
S244 | Phosphorylation | score1 | PhosphoSitePlus | |||
T350 | Phosphorylation | score1 | PhosphoSitePlus | |||
T354 | O-Glycosylation | score3 | GlyGen | 23301498, 30379171, 35289036, ... | ||
T354 | Phosphorylation | score1 | PhosphoSitePlus | |||
T355 | O-Glycosylation | score3 | GlyGen | 23301498, 30379171, 35289036, ... | ||
T355 | Phosphorylation | score1 | PhosphoSitePlus | |||
S359 | Phosphorylation | score1 | PhosphoSitePlus | |||
S372 | Phosphorylation | P23443 (RPS6KB1) | score4 | neXtProt PhosphoSitePlus Signor UniProt | 18669648, 17936702, 23186163, ... | |
T373 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S375 | Phosphorylation | score1 | PhosphoSitePlus | |||
S378 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y403 | Phosphorylation | score1 | PhosphoSitePlus | |||
S408 | Phosphorylation | score1 | PhosphoSitePlus | |||
S412 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 23667685 | ||
S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
S421 | Phosphorylation | score1 | PhosphoSitePlus | |||
S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
S440 | Phosphorylation | score1 | PhosphoSitePlus | |||
S442 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23667685, 23186163 | ||
T447 | Phosphorylation | score1 | PhosphoSitePlus | |||
S449 | Phosphorylation | score1 | PhosphoSitePlus | |||
S471 | Phosphorylation | score1 | PhosphoSitePlus | |||
T473 | Phosphorylation | score1 | PhosphoSitePlus | |||
T480 | Phosphorylation | score1 | PhosphoSitePlus | |||
S488 | Phosphorylation | score1 | PhosphoSitePlus | |||
T492 | Phosphorylation | score1 | PhosphoSitePlus | |||
S516 | O-Glycosylation | score3 | GlyGen | 23301498, 30379171, 35289036, ... |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T241 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
T242 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
S243 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
S244 | Phosphorylation | score0 | HPRD | 19651622, 17081983, 20068231 | ||
S372 | Phosphorylation | score0 | HPRD | 18669648, 20068231 | ||
S442 | Phosphorylation | score0 | HPRD | 18669648 | ||
S488 | Phosphorylation | score0 | HPRD | 20068231 | ||
T492 | Phosphorylation | score0 | HPRD | 20068231 |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | O94763 (URI1) | T241 | P19388 (POLR2E) | inhibited_association | eFIP | 23667685 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S13 | P13 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S243 | F243 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
T354 | I354 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S372 | C372 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S378 | C378 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] | |
S408 | F408 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S440 | T440 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
S516 | T516 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
S516 | C516 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |