iPTMnet Report for O94760 (DDAH1)
Protein Information
| UniProt AC / UniProt ID | O94760 / DDAH1_HUMAN |
| Protein Name | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 |
| Gene Name | Name: DDAH1 Synonyms:DDAH; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O94760 |
| PRO Name | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (human) |
| Definition | An N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 that is encoded in the genome of human. |
| Short Label | hDDAH1 |
| Category | organism-gene |
O94760 (DDAH1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score3 | UniProt | 19413330, 9874257 | ||
| K34 | Acetylation | score1 | PhosphoSitePlus | |||
| K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S97 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C222 | S-Nitrosylation | score2 | dbSNO | 22178444, 12441345 | ||
| K247 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S261 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C274 | S-Nitrosylation | score2 | dbSNO | 22178444, 12441345 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K34 | E34 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| K247 | N247 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |
DAG View