iPTMnet Report for O75828 (CBR3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75828 / CBR3_HUMAN
Protein Name Carbonyl reductase [NADPH] 3
Gene Name Name: CBR3
Synonyms:SDR21C2;
Organism Homo sapiens (Human)

PRO ID PR:O75828
DAG View
PRO Name carbonyl reductase [NADPH] 3 (human)
Definition A carbonyl reductase [NADPH] 3 that is encoded in the genome of human.
Short Label hCBR3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75828 (CBR3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T11 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus
S56 Phosphorylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
K173 Acetylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
C226 S-Nitrosylation dbSNO 19483679
C227 S-Nitrosylation dbSNO 19483679
S240 Phosphorylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T11 I11 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S30 F30 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S56 R56 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
C226 G226 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]