iPTMnet Report for O75807 (PPP1R15A)
Protein Information
UniProt AC / UniProt ID | O75807 / PR15A_HUMAN |
Protein Name | Protein phosphatase 1 regulatory subunit 15A |
Gene Name | Name: PPP1R15A Synonyms:GADD34; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75807 |
PRO Name | protein phosphatase 1 regulatory subunit 15A (human) |
Definition | A protein phosphatase 1 regulatory subunit 15A that is encoded in the genome of human. |
Short Label | hPPP1R15A |
Category | organism-gene |
O75807 (PPP1R15A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S143 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
S249 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y262 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 24092754 | ||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score1 | PhosphoSitePlus | |||
K315 | Acetylation | score1 | PhosphoSitePlus | |||
K322 | Acetylation | score1 | PhosphoSitePlus | |||
Y391 | Phosphorylation | score2 | UniProt | 24092754 | ||
T422 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y434 | Phosphorylation | score2 | UniProt | 24092754 | ||
Y512 | Phosphorylation | score2 | UniProt | 24092754 | ||
T540 | Phosphorylation | score1 | PhosphoSitePlus | |||
K552 | Ubiquitination | score1 | PhosphoSitePlus | |||
S559 | Phosphorylation | score1 | IEDB | 35494241 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S249 | F249 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K315 | N315 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
Y391 | C391 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
Y434 | C434 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |