iPTMnet Report for O75794 (CDC123)
Protein Information
UniProt AC / UniProt ID | O75794 / CD123_HUMAN |
Protein Name | Cell division cycle protein 123 homolog |
Gene Name | Name: CDC123 Synonyms:C10orf7,D123; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75794 |
PRO Name | cell division cycle protein 123 homolog (human) |
Definition | A cell division cycle protein 123 that is encoded in the genome of human. |
Short Label | hCDC123 |
Category | organism-gene |
O75794 (CDC123) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C9 | Methylation | score1 | IEDB | 31844290 | ||
K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
K35 | Ubiquitination | score1 | PhosphoSitePlus | |||
S60 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 18452278 | ||
S70 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 18452278 | ||
K104 | Ubiquitination | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
K168 | Ubiquitination | score1 | PhosphoSitePlus | |||
C170 | Methylation | score1 | IEDB | 31844290 | ||
C180 | Methylation | score1 | IEDB | 31844290 | ||
K186 | Ubiquitination | score1 | PhosphoSitePlus | |||
K204 | Ubiquitination | score1 | PhosphoSitePlus | |||
K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y223 | Phosphorylation | score1 | PhosphoSitePlus | |||
S299 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y301 | Phosphorylation | score1 | PhosphoSitePlus | |||
S303 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y304 | Phosphorylation | score1 | PhosphoSitePlus | |||
K308 | Ubiquitination | score1 | PhosphoSitePlus | |||
K321 | Ubiquitination | score1 | PhosphoSitePlus | |||
K327 | Ubiquitination | score1 | PhosphoSitePlus | |||
K329 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K135 | N135 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
Y304 | H304 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |