iPTMnet Report for O75604 (USP2)
Protein Information
| UniProt AC / UniProt ID | O75604 / UBP2_HUMAN |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 2 |
| Gene Name | Name: USP2 Synonyms:UBP41; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O75604 |
| PRO Name | ubiquitin carboxyl-terminal hydrolase 2 (human) |
| Definition | A ubiquitin carboxyl-terminal hydrolase 2 that is encoded in the genome of human. |
| Short Label | hUSP2 |
| Category | organism-gene |
DAG ViewO75604 (USP2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T137 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S142 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T175 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y403 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S409 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y596 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S38 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T39 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S34 | F34 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
| S34 | Y34 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| T39 | A39 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T39 | P39 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T175 | M175 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
| S225 | G225 | Biomuta | DOID:363 / uterine cancer [ cosmic ] |
