iPTMnet Report for O75487 (GPC4)
Protein Information
UniProt AC / UniProt ID | O75487 / GPC4_HUMAN |
Protein Name | Glypican-4 precursor |
Gene Name | Name: GPC4 ORFNames:UNQ474/PRO937; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75487 |
PRO Name | glypican-4 (human) |
Definition | A glypican-4 that is encoded in the genome of human. |
Short Label | hGPC4 |
Category | organism-gene |
O75487 (GPC4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S39 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y186 | Phosphorylation | score1 | PhosphoSitePlus | |||
S357 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692 | ||
T375 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171, 25813380 | ||
T376 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
T380 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
S381 | O-Glycosylation | score1 | GlyGen | 25813380 | ||
T472 | Phosphorylation | score1 | PhosphoSitePlus | |||
S473 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S39 | P39 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] | |
S357 | P357 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T375 | N375 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T376 | I376 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T380 | I380 | Biomuta | DOID:4362 / cervical cancer [ cosmic ] |