iPTMnet Report for O75439 (PMPCB)
Protein Information
UniProt AC / UniProt ID | O75439 / MPPB_HUMAN |
Protein Name | Mitochondrial-processing peptidase subunit beta precursor |
Gene Name | Name: PMPCB Synonyms:MPPB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75439 |
PRO Name | mitochondrial-processing peptidase subunit beta (human) |
Definition | A mitochondrial-processing peptidase subunit beta that is encoded in the genome of human. |
Short Label | hPMPCB |
Category | organism-gene |
O75439 (PMPCB) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S11 | Phosphorylation | score1 | PhosphoSitePlus | |||
S12 | Phosphorylation | score1 | PhosphoSitePlus | |||
S44 | Phosphorylation | score1 | PhosphoSitePlus | |||
T45 | Phosphorylation | score1 | PhosphoSitePlus | |||
T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
T58 | Phosphorylation | score1 | PhosphoSitePlus | |||
C62 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
T111 | O-Glycosylation | score1 | GlyGen | 36580660, 30379171, 34229054, ... | ||
Y133 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y141 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y142 | Phosphorylation | score1 | PhosphoSitePlus | |||
K148 | Ubiquitination | score1 | PhosphoSitePlus | |||
T205 | Phosphorylation | score1 | PhosphoSitePlus | |||
T215 | O-Glycosylation | score1 | GlyGen | 36580660, 30379171, 34229054, ... | ||
K219 | Ubiquitination | score1 | PhosphoSitePlus | |||
S220 | O-Glycosylation | score1 | GlyGen | 33465208 | ||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y229 | Phosphorylation | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
C419 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
C454 | Methylation | score1 | IEDB | 31844290 | ||
K472 | Ubiquitination | score1 | PhosphoSitePlus | |||
K478 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C62 | Y62 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
Y133 | C133 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
Y141 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y142 | H142 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] |