iPTMnet Report for O75398 (DEAF1)
Protein Information
UniProt AC / UniProt ID | O75398 / DEAF1_HUMAN |
Protein Name | Deformed epidermal autoregulatory factor 1 homolog |
Gene Name | Name: DEAF1 Synonyms:SPN,ZMYND5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75398 |
PRO Name | deformed epidermal autoregulatory factor 1 homolog (human) |
Definition | A deformed epidermal autoregulatory factor 1 that is encoded in the genome of human. |
Short Label | hDEAF1 |
Category | organism-gene |
O75398 (DEAF1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
T171 | Phosphorylation | score1 | PhosphoSitePlus | |||
S176 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15302935, 23186163 | ||
T179 | Phosphorylation | score1 | PhosphoSitePlus | |||
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
S211 | Phosphorylation | score1 | PhosphoSitePlus | |||
T312 | Phosphorylation | score1 | PhosphoSitePlus | |||
S318 | Phosphorylation | score1 | PhosphoSitePlus | |||
T432 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S448 | Phosphorylation | score1 | PhosphoSitePlus | |||
K478 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y483 | Phosphorylation | score1 | PhosphoSitePlus | |||
T488 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T171 | P171 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
K191 | E191 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T312 | P312 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T312 | I312 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S318 | F318 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S318 | T318 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |