iPTMnet Report for O75346 (ZNF253)
Protein Information
UniProt AC / UniProt ID | O75346 / ZN253_HUMAN |
Protein Name | Zinc finger protein 253 |
Gene Name | Name: ZNF253 Synonyms:BMZF1,ZNF411; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75346 |
PRO Name | zinc finger protein 253 (human) |
Definition | A zinc finger protein 253 that is encoded in the genome of human. |
Short Label | hZNF253 |
Category | organism-gene |
O75346 (ZNF253) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C20 | Methylation | score1 | IEDB | 31844290 | ||
S48 | Phosphorylation | score1 | PhosphoSitePlus | |||
C146 | Methylation | score1 | IEDB | 31844290 | ||
T188 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
T189 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
T195 | Phosphorylation | score1 | PhosphoSitePlus | |||
K198 | Sumoylation | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
T223 | Phosphorylation | score1 | PhosphoSitePlus | |||
K226 | Sumoylation | score1 | PhosphoSitePlus | |||
K226 | Ubiquitination | score1 | PhosphoSitePlus | |||
K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
T251 | Phosphorylation | score1 | PhosphoSitePlus | |||
K254 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Sumoylation | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
K263 | Ubiquitination | score1 | PhosphoSitePlus | |||
T279 | Phosphorylation | score1 | PhosphoSitePlus | |||
K282 | Sumoylation | score1 | PhosphoSitePlus | |||
K282 | Ubiquitination | score1 | PhosphoSitePlus | |||
K285 | Sumoylation | score1 | PhosphoSitePlus | |||
K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
K319 | Acetylation | score1 | PhosphoSitePlus | |||
T335 | Phosphorylation | score1 | PhosphoSitePlus | |||
K338 | Ubiquitination | score1 | PhosphoSitePlus | |||
K341 | Sumoylation | score1 | PhosphoSitePlus | |||
K341 | Ubiquitination | score1 | PhosphoSitePlus | |||
T363 | Phosphorylation | score1 | PhosphoSitePlus | |||
K366 | Ubiquitination | score1 | PhosphoSitePlus | |||
K388 | Ubiquitination | score1 | PhosphoSitePlus | |||
T391 | Phosphorylation | score1 | PhosphoSitePlus | |||
K397 | Ubiquitination | score1 | PhosphoSitePlus | |||
T417 | Phosphorylation | score1 | PhosphoSitePlus | |||
T419 | Phosphorylation | score1 | PhosphoSitePlus | |||
K422 | Ubiquitination | score1 | PhosphoSitePlus | |||
K425 | Sumoylation | score1 | PhosphoSitePlus | |||
K425 | Ubiquitination | score1 | PhosphoSitePlus | |||
S432 | Phosphorylation | score1 | PhosphoSitePlus | |||
T434 | Phosphorylation | score1 | PhosphoSitePlus | |||
S436 | Phosphorylation | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
T438 | Phosphorylation | score1 | PhosphoSitePlus | |||
T441 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
T447 | Phosphorylation | score1 | PhosphoSitePlus | |||
K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
K453 | Sumoylation | score1 | PhosphoSitePlus | |||
K453 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C146 | Y146 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K248 | R248 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
K248 | I248 | Biomuta | [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
K257 | T257 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K341 | R341 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
T417 | I417 | Biomuta | DOID:3571 / liver cancer [ cosmic ] DOID:2998 / testicular cancer [ cosmic ] | |
K422 | R422 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S437 | * | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
K453 | R453 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] |