iPTMnet Report for O75335 (PPFIA4)
Protein Information
UniProt AC / UniProt ID | O75335 / LIPA4_HUMAN |
Protein Name | Liprin-alpha-4 |
Gene Name | Name: PPFIA4 Synonyms:KIAA0897; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75335 |
PRO Name | liprin-alpha-4 (human) |
Definition | A liprin-alpha-4 that is encoded in the genome of human. |
Short Label | hPPFIA4 |
Category | organism-gene |
O75335 (PPFIA4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T212 | Phosphorylation | score1 | PhosphoSitePlus | |||
K447 | Ubiquitination | score1 | PhosphoSitePlus | |||
S520 | Phosphorylation | score1 | PhosphoSitePlus | |||
T609 | O-Glycosylation | score1 | GlyGen | 30379171, 28657654 | ||
S684 | Phosphorylation | score1 | PhosphoSitePlus | |||
S700 | Phosphorylation | score1 | PhosphoSitePlus | |||
S703 | Phosphorylation | score1 | PhosphoSitePlus | |||
S704 | Phosphorylation | score1 | PhosphoSitePlus | |||
K751 | Acetylation | score1 | PhosphoSitePlus | |||
K754 | Acetylation | score1 | PhosphoSitePlus | |||
S755 | Phosphorylation | score1 | PhosphoSitePlus | |||
S756 | Phosphorylation | score1 | PhosphoSitePlus | |||
S866 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1103 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1120 | Phosphorylation | score1 | PhosphoSitePlus | |||
R1133 | Methylation | score1 | PhosphoSitePlus | |||
S1151 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1152 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T609 | A609 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S703 | F703 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S704 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] | |
K751 | N751 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
S866 | L866 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
R1133 | C1133 | Biomuta | DOID:363 / uterine cancer [ icgc ] |