iPTMnet Report for O75157 (TSC22D2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75157 / T22D2_HUMAN
Protein Name TSC22 domain family protein 2
Gene Name Name: TSC22D2
Synonyms:KIAA0669;
Organism Homo sapiens (Human)

PRO ID PR:O75157
DAG View
PRO Name TSC22 domain family protein 2 (human)
Definition A TSC22 domain family protein 2 that is encoded in the genome of human.
Short Label hTSC22D2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75157 (TSC22D2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y57 Phosphorylation PhosphoSitePlus
C63 S-Nitrosylation dbSNO 26338901
S171 Phosphorylation PhosphoSitePlus
T181 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
S205 Phosphorylation PhosphoSitePlus
S206 Phosphorylation PhosphoSitePlus
T207 Phosphorylation PhosphoSitePlus
S548 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
S550 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
S550 Phosphorylation phospho.ELM 18669648
S551 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
S552 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
T570 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
S571 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
S575 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
S598 Phosphorylation PhosphoSitePlus
S607 Phosphorylation PhosphoSitePlus
K698 Ubiquitination PhosphoSitePlus
Y703 Phosphorylation PhosphoSitePlus
K713 Ubiquitination PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
S778 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
S779 O-Glycosylation GlyGen 23301498, 33214551, 34725712, ...34019948, 29351928, 35132862
Site PTM Type PTM Enzyme Score Source PMID
S550 Phosphorylation HPRD 18669648
S598 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S205 G205 Biomuta DOID:3571 / liver cancer [ cosmic ]
S205 N205 Biomuta [ cosmic ]
S206 I206 Biomuta DOID:363 / uterine cancer [ icgc ]
S206 R206 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T207 A207 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T570 P570 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
T570 R570 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S724 C724 Biomuta DOID:1324 / lung cancer [ cosmic ]