iPTMnet Report for O75145 (PPFIA3)
Protein Information
UniProt AC / UniProt ID | O75145 / LIPA3_HUMAN |
Protein Name | Liprin-alpha-3 |
Gene Name | Name: PPFIA3 Synonyms:KIAA0654; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O75145 |
PRO Name | liprin-alpha-3 (human) |
Definition | A liprin-alpha-3 that is encoded in the genome of human. |
Short Label | hPPFIA3 |
Category | organism-gene |
O75145 (PPFIA3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S17 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
T55 | Phosphorylation | score1 | PhosphoSitePlus | |||
S75 | Phosphorylation | score1 | PhosphoSitePlus | |||
C122 | Methylation | score1 | IEDB | 31844290 | ||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S142 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T195 | Phosphorylation | score1 | PhosphoSitePlus | |||
S207 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19690332 | ||
T220 | Phosphorylation | score1 | PhosphoSitePlus | |||
S231 | Phosphorylation | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
T272 | Phosphorylation | score1 | PhosphoSitePlus | |||
K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y505 | Phosphorylation | score1 | PhosphoSitePlus | |||
S508 | Phosphorylation | score1 | PhosphoSitePlus | |||
S512 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y533 | Phosphorylation | score1 | PhosphoSitePlus | |||
S537 | Phosphorylation | score1 | PhosphoSitePlus | |||
S645 | Phosphorylation | score1 | PhosphoSitePlus | |||
S683 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T689 | Phosphorylation | score1 | PhosphoSitePlus | |||
T714 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 19690332 | ||
T718 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S721 | Phosphorylation | score1 | PhosphoSitePlus | |||
S765 | Phosphorylation | score1 | PhosphoSitePlus | |||
S766 | Phosphorylation | score1 | PhosphoSitePlus | |||
S786 | Phosphorylation | score1 | PhosphoSitePlus | |||
K807 | Ubiquitination | score1 | PhosphoSitePlus | |||
K821 | Ubiquitination | score1 | PhosphoSitePlus | |||
K866 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1033 | O-Glycosylation | score1 | GlyGen | 30379171, 28657654 | ||
S1105 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1112 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1122 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1123 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1129 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1164 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K1171 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S264 | R264 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S264 | N264 | Biomuta | DOID:363 / uterine cancer [ icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
K450 | N450 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y533 | C533 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S645 | L645 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T718 | N718 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S765 | L765 | Biomuta | DOID:1612 / breast cancer [ icgc ] DOID:1324 / lung cancer [ cosmic ] | |
K807 | Q807 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S1164 | F1164 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
S1164 | Y1164 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |