iPTMnet Report for O75113 (N4BP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O75113 / N4BP1_HUMAN
Protein Name NEDD4-binding protein 1
Gene Name Name: N4BP1
Synonyms:KIAA0615;
Organism Homo sapiens (Human)

PRO ID PR:O75113
DAG View
PRO Name NEDD4-binding protein 1 (human)
Definition A NEDD4-binding protein 1 that is encoded in the genome of human.
Short Label hN4BP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75113 (N4BP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
S150 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T172 O-Glycosylation GlyGen 23301498, 29351928, 30379171, ...32574038, 30059200, 35254053, 35132862, 31492838, 30620550
T180 O-Glycosylation GlyGen 23301498, 29351928, 30379171, ...32574038, 30059200, 35254053, 35132862, 31492838, 30620550
S226 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
K239 Ubiquitination PhosphoSitePlus
T242 Phosphorylation PhosphoSitePlus   UniProt 23186163
S245 Phosphorylation PhosphoSitePlus
T248 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
S256 Phosphorylation HPRD   phospho.ELM 18669648
S258 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
T270 Phosphorylation PhosphoSitePlus
C282 Methylation IEDB 31844290
S288 Phosphorylation HPRD   IEDB   PhosphoSitePlus 27920218, 20166139, 19651622, ...18212344
S290 Phosphorylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
S300 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231, 23186163, 19690332, ...24275569
S335 Phosphorylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
T401 Phosphorylation PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
Y415 Phosphorylation PhosphoSitePlus
S416 O-Glycosylation GlyGen 23301498, 29351928, 30379171, ...32574038, 30059200, 35254053, 35132862, 31492838, 30620550
S416 Phosphorylation PhosphoSitePlus
S417 O-Glycosylation GlyGen 30620550
S417 Phosphorylation PhosphoSitePlus
T418 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
T426 Phosphorylation PhosphoSitePlus
K428 Ubiquitination PhosphoSitePlus
K429 Ubiquitination PhosphoSitePlus
K441 Ubiquitination PhosphoSitePlus
K448 Sumoylation PhosphoSitePlus
K448 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K471 Ubiquitination PhosphoSitePlus
T489 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S495 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
S500 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
R509 Methylation PhosphoSitePlus
R517 Methylation PhosphoSitePlus
K539 Ubiquitination PhosphoSitePlus
S554 Phosphorylation PhosphoSitePlus
S559 Phosphorylation PhosphoSitePlus
T560 Phosphorylation PhosphoSitePlus
S562 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
K601 Ubiquitination PhosphoSitePlus
K605 Ubiquitination PhosphoSitePlus
K609 Ubiquitination PhosphoSitePlus
K618 Ubiquitination PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
S734 Phosphorylation PhosphoSitePlus
K773 Ubiquitination PhosphoSitePlus
T802 O-Glycosylation GlyGen 23301498, 29351928, 30379171, ...32574038, 30059200, 35254053, 35132862, 31492838, 30620550
S806 O-Glycosylation GlyGen 23301498, 29351928, 30379171, ...32574038, 30059200, 35254053, 35132862, 31492838, 30620550
T807 O-Glycosylation GlyGen 23301498, 29351928, 30379171, ...32574038, 30059200, 35254053, 35132862, 31492838, 30620550
T813 O-Glycosylation GlyGen 23301498, 29351928, 30379171, ...32574038, 30059200, 35254053, 35132862, 31492838, 30620550
S838 Phosphorylation PhosphoSitePlus
K863 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K144 N144 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S245 P245 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S245 F245 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S258 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S300 F300 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K366 N366 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y415 D415 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y415 H415 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S416 N416 Biomuta DOID:363 / uterine cancer [ icgc ]
S416 I416 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T426 N426 Biomuta DOID:3571 / liver cancer [ cosmic ]
K448 R448 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S493 P493 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S500 R500 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S562 Y562 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S579 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T813 A813 Biomuta DOID:10534 / stomach cancer [ cosmic ]