Protein Information

Cytoscape View


UniProt AC / UniProt ID O75084 / FZD7_HUMAN
Protein Name Frizzled-7 precursor
Gene Name Name: FZD7
Organism Homo sapiens (Human)

PRO ID PR:O75084
DAG View
PRO Name frizzled-7 (human)
Definition A frizzled-7 that is encoded in the genome of human.
Short Label hFZD7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O75084 (FZD7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
S27 Phosphorylation PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
S42 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
K137 Ubiquitination PhosphoSitePlus
T191 O-Glycosylation GlyGen 30459171
S550 Phosphorylation RLIMS-P 17273804
S556 Phosphorylation RLIMS-P 17273804
S568 Phosphorylation PhosphoSitePlus
K569 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S27 P27 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K137 N137 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T191 S191 Biomuta DOID:1324 / lung cancer [ cosmic ]
S556 L556 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]