iPTMnet Report for O60939 (SCN2B)
Protein Information
UniProt AC / UniProt ID | O60939 / SCN2B_HUMAN |
Protein Name | Sodium channel subunit beta-2 precursor |
Gene Name | Name: SCN2B ORFNames:UNQ326/PRO386; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60939 |
PRO Name | sodium channel subunit beta-2 (human) |
Definition | A sodium channel subunit beta-2 that is encoded in the genome of human. |
Short Label | hSCN2B |
Category | organism-gene |
O60939 (SCN2B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N66 | N-Glycosylation | score3 | GlyGen UniProt | 30765606 | ||
S156 | Phosphorylation | score1 | PhosphoSitePlus | |||
T157 | Phosphorylation | score1 | PhosphoSitePlus | |||
S165 | Phosphorylation | score1 | PhosphoSitePlus | |||
S192 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18510355 | ||
T204 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N66 | S66 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
S156 | F156 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T157 | M157 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S165 | F165 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T204 | M204 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] |