iPTMnet Report for O60906 (SMPD2)
Protein Information
UniProt AC / UniProt ID | O60906 / NSMA_HUMAN |
Protein Name | Sphingomyelin phosphodiesterase 2 |
Gene Name | Name: SMPD2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60906 |
PRO Name | sphingomyelin phosphodiesterase 2 (human) |
Definition | A sphingomyelin phosphodiesterase 2 that is encoded in the genome of human. |
Short Label | hSMPD2 |
Category | organism-gene |
O60906 (SMPD2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S86 | Phosphorylation | score1 | IEDB | 35494241 | ||
K208 | Ubiquitination | score1 | PhosphoSitePlus | |||
S270 | Phosphorylation | score0 | RLIMS-P | 25168245 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K208 | N208 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |