iPTMnet Report for O60879 (DIAPH2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60879 / DIAP2_HUMAN
Protein Name Protein diaphanous homolog 2
Gene Name Name: DIAPH2
Synonyms:DIA;
Organism Homo sapiens (Human)

PRO ID PR:O60879
DAG View
PRO Name protein diaphanous homolog 2 (human)
Definition A protein diaphanous homolog 2 that is encoded in the genome of human.
Short Label hDIAPH2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60879 (DIAPH2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378
S15 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S61 Phosphorylation PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
Y94 Phosphorylation PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K124 Acetylation PhosphoSitePlus
K130 Acetylation PhosphoSitePlus
C159 S-Nitrosylation dbSNO 26338901
S196 Phosphorylation Signor 21397845
S196 Phosphorylation Q96GD4 (AURKB) Signor 21397845
K238 Ubiquitination PhosphoSitePlus
T509 Phosphorylation PhosphoSitePlus
Y632 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S637 Phosphorylation PhosphoSitePlus
K700 Acetylation PhosphoSitePlus
K701 Acetylation PhosphoSitePlus
K970 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y632 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
Y632 Phosphorylation HPRD 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y94 C94 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K238 I238 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K238 N238 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K701 R701 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K970 N970 Biomuta DOID:3571 / liver cancer [ cosmic ]