iPTMnet Report for O60828 (PQBP1)
Protein Information
UniProt AC / UniProt ID | O60828 / PQBP1_HUMAN |
Protein Name | Polyglutamine-binding protein 1 |
Gene Name | Name: PQBP1 Synonyms:NPW38;ORFNames:JM26; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60828 |
PRO Name | polyglutamine-binding protein 1 (human) |
Definition | A polyglutamine-binding protein 1 that is encoded in the genome of human. |
Short Label | hPQBP1 |
Category | organism-gene |
O60828 (PQBP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R10 | Methylation | score1 | PhosphoSitePlus | |||
K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y33 | Phosphorylation | score1 | PhosphoSitePlus | |||
C60 | Methylation | score1 | IEDB | 31844290 | ||
S77 | Phosphorylation | score1 | PhosphoSitePlus | |||
S94 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
S95 | Phosphorylation | score1 | PhosphoSitePlus | |||
S110 | Phosphorylation | score1 | PhosphoSitePlus | |||
S120 | O-Glycosylation | score1 | GlyGen | 33214551, 30379171, 35254053, ... | ||
Y146 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y187 | Phosphorylation | score1 | PhosphoSitePlus | |||
K191 | Methylation | score1 | PhosphoSitePlus | |||
Y209 | Phosphorylation | score1 | PhosphoSitePlus | |||
S210 | Phosphorylation | score1 | PhosphoSitePlus | |||
R214 | Methylation | score1 | PhosphoSitePlus | |||
T219 | Phosphorylation | score1 | PhosphoSitePlus | |||
T229 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
T233 | O-Glycosylation | score1 | GlyGen | 33214551, 30379171, 35254053, ... | ||
Y245 | Phosphorylation | score1 | phospho.ELM | 18669648 | ||
S247 | O-Glycosylation | score1 | GlyGen | 31373491 | ||
S247 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S94 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y245 | Phosphorylation | score0 | HPRD | 18669648 | ||
S247 | Phosphorylation | score0 | HPRD | 18669648, 20068231 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y33 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R10 | H10 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S110 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y209 | H209 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
T219 | I219 | Biomuta | [ cosmic ] |