iPTMnet Report for O60711 (LPXN)
Protein Information
UniProt AC / UniProt ID | O60711 / LPXN_HUMAN |
Protein Name | Leupaxin |
Gene Name | Name: LPXN Synonyms:LDLP; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60711 |
PRO Name | leupaxin (human) |
Definition | A leupaxin that is encoded in the genome of human. |
Short Label | hLPXN |
Category | organism-gene |
O60711 (LPXN) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378, 25944712 | ||
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
S19 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15144186 | ||
Y22 | Phosphorylation | score4 | phospho.ELM PhosphoSitePlus UniProt | 15592455, 20543562, 15144186, ... | ||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
S34 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y62 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 20543562 | ||
Y72 | Phosphorylation | P07948 (LYN) | score4 | neXtProt PhosphoSitePlus RLIMS-P Signor UniProt | 20543562, 17640867 | |
S81 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
K106 | Ubiquitination | score1 | PhosphoSitePlus | |||
K121 | Ubiquitination | score1 | PhosphoSitePlus | |||
K125 | Ubiquitination | score1 | PhosphoSitePlus | |||
S127 | Phosphorylation | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
K149 | Ubiquitination | score1 | PhosphoSitePlus | |||
K157 | Ubiquitination | score1 | PhosphoSitePlus | |||
S170 | Phosphorylation | score1 | PhosphoSitePlus | |||
S187 | Phosphorylation | score1 | PhosphoSitePlus | |||
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score1 | PhosphoSitePlus | |||
C199 | Methylation | score1 | IEDB | 31844290 | ||
Y203 | Phosphorylation | score1 | PhosphoSitePlus | |||
S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
C211 | Methylation | score1 | IEDB | 31844290 | ||
Y213 | Phosphorylation | score1 | PhosphoSitePlus | |||
C214 | Methylation | score1 | IEDB | 31844290 | ||
C258 | Methylation | score1 | IEDB | 31844290 | ||
K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
S267 | Phosphorylation | score1 | PhosphoSitePlus | |||
C293 | Methylation | score1 | IEDB | 31844290 | ||
T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
S342 | Phosphorylation | score1 | PhosphoSitePlus | |||
K364 | Ubiquitination | score1 | PhosphoSitePlus | |||
K373 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y375 | Phosphorylation | score1 | PhosphoSitePlus | |||
K382 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S81 | L81 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
K106 | R106 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
K121 | N121 | Biomuta | DOID:263 / kidney cancer [ cosmic, icgc ] | |
S127 | F127 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S194 | G194 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
S208 | P208 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
Y213 | D213 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S267 | * | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
S267 | L267 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T327 | M327 | Biomuta | DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] | |
K364 | N364 | Biomuta | DOID:2021 / placenta cancer [ cosmic ] | |
Y375 | C375 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |