iPTMnet Report for O60704 (TPST2)
Protein Information
UniProt AC / UniProt ID | O60704 / TPST2_HUMAN |
Protein Name | Protein-tyrosine sulfotransferase 2 |
Gene Name | Name: TPST2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60704 |
PRO Name | protein-tyrosine sulfotransferase 2 (human) |
Definition | A protein-tyrosine sulfotransferase 2 that is encoded in the genome of human. |
Short Label | hTPST2 |
Category | organism-gene |
O60704 (TPST2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N58 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
K158 | Ubiquitination | score1 | PhosphoSitePlus | |||
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
T194 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y222 | Phosphorylation | score1 | PhosphoSitePlus | |||
S278 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
S285 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 25813380 | ||
T286 | O-Glycosylation | score2 | GlyGen PhosphoSitePlus | 23584533, 30459171, 25813380 | ||
K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
N366 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N368 | N-Glycosylation | score1 | GlyGen | 24190977 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N58 | S58 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S191 | F191 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
K291 | E291 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |