iPTMnet Report for O60610 (DIAPH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60610 / DIAP1_HUMAN
Protein Name Protein diaphanous homolog 1
Gene Name Name: DIAPH1
Synonyms:DIAP1;
Organism Homo sapiens (Human)

PRO ID PR:O60610
DAG View
PRO Name protein diaphanous homolog 1 (human)
Definition A protein diaphanous homolog 1 that is encoded in the genome of human.
Short Label hDIAPH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60610 (DIAPH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378, 22223895
S7 Phosphorylation PhosphoSitePlus   UniProt 23186163
R12 Methylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
S22 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S28 Phosphorylation PhosphoSitePlus
K35 Acetylation PhosphoSitePlus
K35 Methylation PhosphoSitePlus
K35 Ubiquitination PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus   UniProt 23186163
K37 Acetylation PhosphoSitePlus
K38 Acetylation PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
K42 Methylation PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
S71 Phosphorylation PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
Y128 Phosphorylation PhosphoSitePlus
Y130 Phosphorylation PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
Y209 Phosphorylation PhosphoSitePlus
K214 Ubiquitination PhosphoSitePlus
K222 Ubiquitination PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
Y374 Phosphorylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
Y424 Phosphorylation PhosphoSitePlus
C437 Methylation IEDB 31844290
S439 O-Glycosylation GlyGen 23301498, 34725712, 29351928, ...35132862, 32119511, 28510447, 29237092
K453 Ubiquitination PhosphoSitePlus
K473 Acetylation PhosphoSitePlus
K476 Acetylation PhosphoSitePlus
K476 Ubiquitination PhosphoSitePlus
K480 Acetylation PhosphoSitePlus
K486 Ubiquitination PhosphoSitePlus
K487 Acetylation PhosphoSitePlus
K487 Ubiquitination PhosphoSitePlus
S490 O-Glycosylation GlyGen 23301498, 34725712, 29351928, ...35132862, 32119511, 28510447, 29237092
K503 Ubiquitination PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
K520 Acetylation PhosphoSitePlus
K520 Ubiquitination PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
S542 Phosphorylation PhosphoSitePlus
K550 Ubiquitination PhosphoSitePlus
T607 Phosphorylation RLIMS-P 30816115
S629 Phosphorylation RLIMS-P 30816115
S640 Phosphorylation RLIMS-P 30816115
S665 Phosphorylation RLIMS-P 30816115
T768 Phosphorylation P06493 (CDK1) PhosphoSitePlus   UniProt 18234856, 23325789
K771 Ubiquitination PhosphoSitePlus
Y773 Phosphorylation PhosphoSitePlus
K774 Ubiquitination PhosphoSitePlus
K786 Ubiquitination PhosphoSitePlus
C796 Methylation IEDB 31844290
K800 Ubiquitination PhosphoSitePlus
K802 Ubiquitination PhosphoSitePlus
K814 Acetylation PhosphoSitePlus
K824 Acetylation PhosphoSitePlus
K824 Ubiquitination PhosphoSitePlus
K830 Acetylation PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
S866 Phosphorylation PhosphoSitePlus
Y871 Phosphorylation PhosphoSitePlus
K1046 Ubiquitination PhosphoSitePlus
S1051 Phosphorylation PhosphoSitePlus
K1057 Acetylation PhosphoSitePlus   UniProt 19608861
K1057 Ubiquitination PhosphoSitePlus
T1091 Phosphorylation PhosphoSitePlus
K1103 Acetylation PhosphoSitePlus   UniProt 19608861
K1103 Ubiquitination PhosphoSitePlus
Y1121 Phosphorylation PhosphoSitePlus
K1128 Acetylation PhosphoSitePlus
K1224 Ubiquitination PhosphoSitePlus
C1227 S-Nitrosylation dbSNO 19483679, 22178444
T1230 O-Glycosylation GlyGen 23301498, 34725712, 29351928, ...35132862, 32119511, 28510447, 29237092
S1231 O-Glycosylation GlyGen 23301498, 34725712, 29351928, ...35132862, 32119511, 28510447, 29237092
S1235 O-Glycosylation GlyGen 23301498, 34725712, 29351928, ...35132862, 32119511, 28510447, 29237092
T1238 Phosphorylation PhosphoSitePlus
K1239 Ubiquitination PhosphoSitePlus
K1249 Ubiquitination PhosphoSitePlus
S1251 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1252 Ubiquitination PhosphoSitePlus
S1254 Phosphorylation PhosphoSitePlus   UniProt 23186163
T1256 Phosphorylation PhosphoSitePlus
K1265 Ubiquitination PhosphoSitePlus
S1272 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation HPRD 19651622, 18669648, 20068231
S861 Phosphorylation HPRD 20068231
S866 Phosphorylation HPRD 20068231
S959 Phosphorylation HPRD 20068231
T961 Phosphorylation HPRD 20068231
T1196 Phosphorylation HPRD 18452278
S1201 Phosphorylation HPRD 18452278
S1272 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
K803 Acetylation PhosphoSitePlus
K805 Acetylation PhosphoSitePlus
K806 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S22 Phosphorylation HPRD 19651622, 18669648, 20068231
S852 Phosphorylation HPRD 20068231
S857 Phosphorylation HPRD 20068231
S950 Phosphorylation HPRD 20068231
T952 Phosphorylation HPRD 20068231
T1187 Phosphorylation HPRD 18452278
S1192 Phosphorylation HPRD 18452278
S1263 Phosphorylation HPRD 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P61586 (RHOA) S188 O60610 (DIAPH1) increased_association eFIP 20591975