iPTMnet Report for O60568 (PLOD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60568 / PLOD3_HUMAN
Protein Name Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 precursor
Gene Name Name: PLOD3
Organism Homo sapiens (Human)

PRO ID PR:O60568
DAG View
PRO Name multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 (human)
Definition A multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 that is encoded in the genome of human.
Short Label hPLOD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60568 (PLOD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S23 Phosphorylation PhosphoSitePlus
S25 O-Glycosylation GlyGen 25813380
S25 Phosphorylation PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
N63 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 30089812, ...24190977
T65 O-Glycosylation GlyGen 35008409, 33214551, 35138101, ...34725712, 35254053, 34019948, 33465208
R76 Methylation PhosphoSitePlus
K127 Acetylation PhosphoSitePlus
K128 Acetylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
T174 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
K186 Ubiquitination PhosphoSitePlus
K207 Ubiquitination PhosphoSitePlus
K215 Ubiquitination PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
R411 Methylation PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
Y444 Phosphorylation PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
N548 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 24190977, ...30089812, 34089345
Y604 O-Glycosylation GlyGen 25813380
K645 Ubiquitination PhosphoSitePlus
S701 O-Glycosylation GlyGen 35008409, 33214551, 35138101, ...34725712, 35254053, 34019948, 33465208
Y730 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N63 N-Glycosylation PRO 29741879


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S25 F25 Biomuta DOID:4159 / skin cancer [ cosmic ]
R76 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
K127 Q127 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T288 A288 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S419 P419 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
K500 N500 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S701 F701 Biomuta DOID:4159 / skin cancer [ cosmic ]