iPTMnet Report for O60508 (CDC40)
Protein Information
UniProt AC / UniProt ID | O60508 / PRP17_HUMAN |
Protein Name | Pre-mRNA-processing factor 17 |
Gene Name | Name: CDC40 Synonyms:EHB3,PRP17,PRPF17; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60508 |
PRO Name | pre-mRNA-processing factor 17 (human) |
Definition | A pre-mRNA-processing factor 17 that is encoded in the genome of human. |
Short Label | hCDC40 |
Category | organism-gene |
O60508 (CDC40) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score0 | HPRD | 20068231 | ||
Y12 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S14 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S16 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 | ||
S18 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S20 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983, 20068231 | ||
S22 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S24 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S27 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S43 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 20068231 | ||
S45 | Phosphorylation | score1 | PhosphoSitePlus | |||
S46 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S49 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 20068231 | ||
S56 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y81 | Phosphorylation | score1 | PhosphoSitePlus | |||
T84 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y85 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y114 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y135 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y137 | Phosphorylation | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
K226 | Acetylation | score1 | PhosphoSitePlus | |||
K228 | Acetylation | score1 | PhosphoSitePlus | |||
C366 | Methylation | score1 | IEDB | 31844290 | ||
C378 | Methylation | score1 | IEDB | 31844290 | ||
K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
K387 | Ubiquitination | score1 | PhosphoSitePlus | |||
K399 | Acetylation | score1 | PhosphoSitePlus | |||
S435 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y12 | C12 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y85 | C85 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y114 | D114 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |