iPTMnet Report for O60493 (SNX3)
Protein Information
UniProt AC / UniProt ID | O60493 / SNX3_HUMAN |
Protein Name | Sorting nexin-3 |
Gene Name | Name: SNX3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60493 |
PRO Name | sorting nexin-3 (human) |
Definition | A sorting nexin-3 that is encoded in the genome of human. |
Short Label | hSNX3 |
Category | organism-gene |
O60493 (SNX3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Ubiquitination | score1 | PRO | ||||
A2 | Acetylation | score1 | UniProt | 19413330, 12665801, 25944712 | ||
K14 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y22 | Phosphorylation | score1 | PhosphoSitePlus | |||
S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
R43 | Methylation | score2 | PhosphoSitePlus UniProt | 24129315 | ||
R45 | Methylation | score1 | PhosphoSitePlus | |||
T47 | Phosphorylation | score1 | PhosphoSitePlus | |||
T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y49 | Phosphorylation | score1 | PhosphoSitePlus | |||
K54 | Ubiquitination | score1 | PhosphoSitePlus | |||
T55 | Phosphorylation | score1 | PhosphoSitePlus | |||
K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
K63 | Ubiquitination | score1 | PhosphoSitePlus | |||
T66 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y71 | Phosphorylation | score1 | PhosphoSitePlus | |||
S72 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163, 16964243, ... | ||
S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
K86 | Sumoylation | score1 | PhosphoSitePlus | |||
K86 | Ubiquitination | score1 | PhosphoSitePlus | |||
K95 | Sumoylation | score1 | PhosphoSitePlus | |||
K95 | Ubiquitination | score1 | PhosphoSitePlus | |||
K119 | Sumoylation | score1 | PhosphoSitePlus | |||
K119 | Ubiquitination | score1 | PhosphoSitePlus | |||
K128 | Sumoylation | score1 | PhosphoSitePlus | |||
K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
K152 | Ubiquitination | score1 | PhosphoSitePlus | |||
S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y154 | Phosphorylation | score1 | PhosphoSitePlus | |||
T155 | Phosphorylation | score1 | PhosphoSitePlus | |||
K158 | Sumoylation | score1 | PhosphoSitePlus | |||
K158 | Ubiquitination | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000049316 (hSNX3/InitMet-/UbiqLys+) | ub | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | E2 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
R43 | L43 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R45 | L45 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S72 | R72 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S79 | R79 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |