iPTMnet Report for O60337 (MARCHF6)
Protein Information
UniProt AC / UniProt ID | O60337 / MARH6_HUMAN |
Protein Name | E3 ubiquitin-protein ligase MARCHF6 |
Gene Name | Name: MARCHF6 Synonyms:KIAA0597,MARCH6,RNF176,TEB4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O60337 |
PRO Name | E3 ubiquitin-protein ligase MARCHF6 (human) |
Definition | An E3 ubiquitin-protein ligase MARCHF6 that is encoded in the genome of human. |
Short Label | hMARCHF6 |
Category | organism-gene |
O60337 (MARCHF6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
S14 | Phosphorylation | score1 | PhosphoSitePlus | |||
T17 | Phosphorylation | score1 | PhosphoSitePlus | |||
K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
T29 | Phosphorylation | score1 | PhosphoSitePlus | |||
S31 | Phosphorylation | score1 | PhosphoSitePlus | |||
K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
K49 | Ubiquitination | score1 | PhosphoSitePlus | |||
K56 | Ubiquitination | score1 | PhosphoSitePlus | |||
C369 | Methylation | score1 | IEDB | 31844290 | ||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y474 | Phosphorylation | score1 | PhosphoSitePlus | |||
K550 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y850 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y874 | Phosphorylation | score1 | PhosphoSitePlus | |||
K878 | Ubiquitination | score1 | PhosphoSitePlus | |||
K881 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y882 | Phosphorylation | score1 | PhosphoSitePlus | |||
K897 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K20 | Q20 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T29 | N29 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
T29 | I29 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y882 | C882 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] |