iPTMnet Report for O43709 (BUD23)
Protein Information
UniProt AC / UniProt ID | O43709 / BUD23_HUMAN |
Protein Name | Probable 18S rRNA (guanine-N(7))-methyltransferase |
Gene Name | Name: BUD23 Synonyms:MERM1,WBSCR22;ORFNames:HUSSY-03,PP3381; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43709 |
PRO Name | probable 18S rRNA (guanine-N(7))-methyltransferase (human) |
Definition | A probable 18S rRNA (guanine-N(7))-methyltransferase that is encoded in the genome of human. |
Short Label | hBUD23 |
Category | organism-gene |
O43709 (BUD23) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
C55 | Methylation | score1 | IEDB | 31844290 | ||
C62 | Methylation | score1 | IEDB | 31844290 | ||
K134 | Ubiquitination | score1 | PhosphoSitePlus | |||
S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
K180 | Ubiquitination | score1 | PhosphoSitePlus | |||
K196 | Ubiquitination | score1 | PhosphoSitePlus | |||
K198 | Methylation | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
S240 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S248 | Phosphorylation | score1 | PhosphoSitePlus | |||
K255 | Ubiquitination | score1 | PhosphoSitePlus | |||
K256 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y272 | Phosphorylation | score1 | PhosphoSitePlus | |||
T273 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K134 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S240 | L240 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S240 | P240 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] | |
S248 | R248 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K256 | N256 | Biomuta | DOID:363 / uterine cancer [ icgc ] |