iPTMnet Report for O43639 (NCK2)
Protein Information
UniProt AC / UniProt ID | O43639 / NCK2_HUMAN |
Protein Name | Cytoplasmic protein NCK2 |
Gene Name | Name: NCK2 Synonyms:GRB4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43639 |
PRO Name | cytoplasmic protein NCK2 (human) |
Definition | A cytoplasmic protein NCK2 that is encoded in the genome of human. |
Short Label | hNCK2 |
Category | organism-gene |
O43639 (NCK2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T2 | Acetylation | score1 | UniProt | 22223895 | ||
T37 | Phosphorylation | score1 | PhosphoSitePlus | |||
T48 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y50 | Phosphorylation | score1 | PhosphoSitePlus | |||
S53 | Phosphorylation | score1 | PhosphoSitePlus | |||
S61 | Phosphorylation | score1 | PhosphoSitePlus | |||
S66 | Phosphorylation | score1 | PhosphoSitePlus | |||
T74 | Phosphorylation | score1 | PhosphoSitePlus | |||
S90 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 23186163, 19664994, 18452278, ... | ||
T92 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 15345747, 18088087, 23186163 | ||
S94 | Phosphorylation | score1 | PhosphoSitePlus | |||
T95 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y99 | Phosphorylation | score1 | PhosphoSitePlus | |||
S104 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y110 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 15570572, 18088087 | ||
S176 | Phosphorylation | score1 | PhosphoSitePlus | |||
S187 | Phosphorylation | score1 | PhosphoSitePlus | |||
S189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y271 | Phosphorylation | score1 | PhosphoSitePlus | |||
S321 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y342 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T92 | M92 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
T95 | M95 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S176 | C176 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S187 | L187 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S270 | I270 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |