Protein Information

Cytoscape View


UniProt AC / UniProt ID O43548 / TGM5_HUMAN
Protein Name Protein-glutamine gamma-glutamyltransferase 5
Gene Name Name: TGM5
Synonyms:TGMX;
Organism Homo sapiens (Human)

PRO ID PR:O43548
DAG View
PRO Name protein-glutamine gamma-glutamyltransferase 5 (human)
Definition A protein-glutamine gamma-glutamyltransferase 5 that is encoded in the genome of human.
Short Label hTGM5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43548 (TGM5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 15290349
S78 Phosphorylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus
S485 Phosphorylation PhosphoSitePlus
S490 Phosphorylation PhosphoSitePlus
S493 O-Glycosylation GlyGen 30379171, 35254053
S498 O-Glycosylation GlyGen 30379171, 35254053
Y575 Phosphorylation PhosphoSitePlus
C577 Methylation IEDB 31844290
Y581 Phosphorylation PhosphoSitePlus
Y587 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:1319 / brain cancer [ cosmic ]
T484 K484 Biomuta DOID:1612 / breast cancer [ cosmic ]
C577 Y577 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y581 D581 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]