iPTMnet Report for O43513 (MED7)
Protein Information
| UniProt AC / UniProt ID | O43513 / MED7_HUMAN |
| Protein Name | Mediator of RNA polymerase II transcription subunit 7 |
| Gene Name | Name: MED7 Synonyms:ARC34,CRSP9; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O43513 |
| PRO Name | mediator of RNA polymerase II transcription subunit 7 (human) |
| Definition | A mediator of RNA polymerase II transcription subunit 7 that is encoded in the genome of human. |
| Short Label | hMED7 |
| Category | organism-gene |
O43513 (MED7) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K185 | Sumoylation | score1 | PhosphoSitePlus | |||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S194 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
| C197 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| T198 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S194 | I194 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
DAG View