iPTMnet Report for O43513 (MED7)
Protein Information
UniProt AC / UniProt ID | O43513 / MED7_HUMAN |
Protein Name | Mediator of RNA polymerase II transcription subunit 7 |
Gene Name | Name: MED7 Synonyms:ARC34,CRSP9; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43513 |
PRO Name | mediator of RNA polymerase II transcription subunit 7 (human) |
Definition | A mediator of RNA polymerase II transcription subunit 7 that is encoded in the genome of human. |
Short Label | hMED7 |
Category | organism-gene |
O43513 (MED7) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K33 | Ubiquitination | score1 | PhosphoSitePlus | |||
K155 | Ubiquitination | score1 | PhosphoSitePlus | |||
K185 | Sumoylation | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
S194 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 19369195 | ||
C197 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
T198 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S194 | I194 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |