iPTMnet Report for O43283 (MAP3K13)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43283 / M3K13_HUMAN
Protein Name Mitogen-activated protein kinase kinase kinase 13
Gene Name Name: MAP3K13
Synonyms:LZK;
Organism Homo sapiens (Human)

PRO ID PR:O43283
DAG View
PRO Name mitogen-activated protein kinase kinase kinase 13 (human)
Definition A mitogen-activated protein kinase kinase kinase 13 that is encoded in the genome of human.
Short Label hMAP3K13
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43283 (MAP3K13) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T54 Phosphorylation PhosphoSitePlus
S59 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
Y483 Phosphorylation PhosphoSitePlus
K502 Acetylation PhosphoSitePlus
Y511 Phosphorylation PhosphoSitePlus
K541 Methylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
S578 Phosphorylation PhosphoSitePlus
S579 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
T797 Phosphorylation PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
S921 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S59 C59 Biomuta DOID:4159 / skin cancer [ cosmic ]
S681 T681 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S811 G811 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S921 Y921 Biomuta DOID:363 / uterine cancer [ icgc ]