iPTMnet Report for O43236 (SEPTIN4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43236 / SEPT4_HUMAN
Protein Name Septin-4
Gene Name Name: SEPTIN4
Synonyms:C17orf47;ORFNames:hucep-7;
Organism Homo sapiens (Human)

PRO ID PR:O43236
DAG View
PRO Name septin-4 (human)
Definition A septin-4 that is encoded in the genome of human.
Short Label hSEPTIN4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43236 (SEPTIN4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S107 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus   UniProt 24275569
S118 Phosphorylation PhosphoSitePlus   UniProt 24275569
Y124 Phosphorylation PhosphoSitePlus
T129 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
S325 Phosphorylation PhosphoSitePlus   UniProt 24275569, 18318008
K456 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S118 Phosphorylation HPRD 18510355
S325 Phosphorylation HPRD 20166139
Site PTM Type PTM Enzyme Score Source PMID
S99 Phosphorylation HPRD 18510355
S306 Phosphorylation HPRD 20166139
Site PTM Type PTM Enzyme Score Source PMID
S99 Phosphorylation HPRD 18510355
Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
T94 Phosphorylation PhosphoSitePlus
S195 Phosphorylation PhosphoSitePlus
Y196 Phosphorylation PhosphoSitePlus
K274 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S117 F117 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y196 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]