iPTMnet Report for O43169 (CYB5B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43169 / CYB5B_HUMAN
Protein Name Cytochrome b5 type B precursor
Gene Name Name: CYB5B
Synonyms:CYB5M,OMB5;
Organism Homo sapiens (Human)

PRO ID PR:O43169
DAG View
PRO Name cytochrome b5 type B (human)
Definition A cytochrome b5 type B that is encoded in the genome of human.
Short Label hCYB5B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43169 (CYB5B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD   PhosphoSitePlus 18491316
S4 Phosphorylation PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S23 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18767875, 23186163
K34 Acetylation PhosphoSitePlus   UniProt 19608861
K34 Ubiquitination PhosphoSitePlus
S37 Phosphorylation HPRD   IEDB   PhosphoSitePlus 27920218, 18669648
K39 Methylation PhosphoSitePlus   UniProt 24129315
K39 Ubiquitination PhosphoSitePlus
K92 Acetylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 F2 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S4 * Biomuta DOID:4362 / cervical cancer [ cosmic ]
S23 * Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ]
K34 N34 Biomuta [ cosmic ] DOID:1115 / sarcoma [ icgc ]